2 March 2021
A national consortium bringing together modellers to produce rigorous predictions for the COVID-19 pandemic and advise UK government bodies will receive £3 million funding from UK Research and Innovation (UKRI).
The JUNIPER consortium (‘Joint UNIversities Pandemic and Epidemiological Research’) brings together leading mathematical and statistical modellers from seven UK universities, including researchers Drs Ellen Brooks Pollock, Hannah Christensen from the NIHR Health Protection Research Unit in Behavioural Science and Evaluation at University of Bristol and Leon Danon from the University of Bristol.
They are developing and using bespoke models to provide predictions and estimates on key questions about the COVID-19 pandemic. These results feed regularly into SPI-M (Scientific Pandemic Infleunza Group on Modelling), the modelling group that provides evidence to the Scientific Advisory Group for Emergencies (SAGE) and the wider UK government.
Examples of modelling the consortium provides to government includes:
- Understanding how new variants are spreading across the UK and developing statistical models to determine whether a new variant is causing more hospitalisations or deaths.
- Forecasting and providing real-time estimates of the R value, using data from many sources such as Pillar 1 and 2 testing, hospital data and mobility data. They are currently providing eight of 12 models contributing real time R estimates that go from SPI-M to SAGE each week.
- Modelling the effectiveness of different testing strategies on virus transmission and suppression, and modelling the effect of vaccinations and predicting outcomes from different scenarios of how to ease lockdown restrictions.
Dr Ellen Brooks Pollock, co-investigator of the consortium, member of SPI-M, SPI-B and SAGE-subgroup on children and schools and Senior Lecturer in Infectious Disease Mathematical Modelling at the University of Bristol, said: "It's exciting to be part of the JUNIPER consortium. Many of the JUNIPER researchers have been working together throughout the pandemic, and this funding award will support those collaborations.
"The work is fast-paced and dynamic, and being part of a group of world-class modellers means that we can draw on a range of expertise. We are recruiting three further postdocs to join the Bristol JUNIPER team, so do get in touch if you are interested."
Dr Leon Danon, member of SPI-M and SAGE-sub-group on social care and Associate Professor in Infectious Disease Modelling and Data Analytics from the University of Bristol, and the Alan Turing Institute, added: "This consortium formalises a long-standing collaboration between the member universities. The funding not only enables us to respond rapidly and robustly to pressing policy questions but also helps develop the scientific legacy of the Covid pandemic."
The consortium, co-led by Professors Julia Gog from the University of Cambridge and Matt Keeling from the University of Warwick, is funded as part of UKRI's COVID-19 Agile Call, which has so far invested more than £150 million in over 400 projects and consortia to address the impacts of the COVID-19 pandemic.
Professor Charlotte Deane, COVID-19 Response Director at UKRI, said: "This consortium enables disease modellers to pool their expertise nationally to increase the scale, speed and quality of their models of policy options and predictions for the pandemic. They’ll provide cutting-edge evidence about the pandemic into the UK government’s decision-making."
The consortium will also proactively generate new model-based predictions and develop the necessary methodology as part of a horizon-scanning process.
The consortium plan to make their models open-source, so scientists worldwide can access them and benefit.
The research groups in the consortium are based at seven universities: University of Bristol, University of Cambridge, University of Exeter, Lancaster University, The University of Manchester, University of Oxford and University of Warwick.
They will work closely with many other organisations and research teams active on COVID-19 research including the Alan Turing Institute, the Royal Statistical Society, Health Data Research UK, Public Health England, the Royal Society’s 'RAMP' initiative and the Isaac Newton Institute for Mathematical Sciences.
About UK Research and Innovation
UK Research and Innovation (UKRI) is the largest public funder of research and innovation in the UK, with a budget of over £8bn. It is composed of seven disciplinary research councils, Innovate UK and Research England.
We operate across the whole country and work with our many partners in higher education, research organisations businesses, government, and charities.
Our vision is for an outstanding research and innovation system in the UK that gives everyone the opportunity to contribute and to benefit, enriching lives locally, nationally and internationally.
Our mission is to convene, catalyse and invest in close collaboration with others to build a thriving, inclusive research and innovation system that connects discovery to prosperity and public good.
About the NIHR Health Protection Research Unit [HPRU] in Behavioural Science and Evaluation at the University of Bristol
The NIHR HPRU in Behavioural Science and Evaluation at University of Bristol is one of 14 HPRUs across England, part of a £58.7 million investment by the NIHR to protect the health of the nation.
The NIHR HPRU in Behavioural Science and Evaluation is a partnership between Public Health England and University of Bristol, in collaboration with MRC Biostatistics Research Unit at the University of Cambridge and University of the West of England.
Each NIHR HPRU undertakes high quality research that is used by PHE to keep the public safe from current and emerging public health threats.
About the NIHR
The National Institute for Health Research (NIHR) is the nation's largest funder of health and care research. The NIHR:
- funds, supports and delivers high quality research that benefits the NHS, public health and social care
- engages and involves patients, carers and the public in order to improve the reach, quality and impact of research
- attracts, trains and supports the best researchers to tackle the complex health and care challenges of the future
- invests in world-class infrastructure and a skilled delivery workforce to translate discoveries into improved treatments and services
- partners with other public funders, charities and industry to maximise the value of research to patients and the economy.
The NIHR was established in 2006 to improve the health and wealth of the nation through research, and is funded by the Department of Health and Social Care. In addition to its national role, the NIHR supports applied health research for the direct and primary benefit of people in low- and middle-income countries, using UK aid from the UK government.