15 September 2020
As universities prepare to welcome students back, infectious disease modelling experts at the University of Bristol have conducted a rapid review and developed a new epidemic model which contributed to evidence considered by SAGE to assess the effectiveness of different interventions that could stop the spread of Sars-CoV-2 in a university setting. The findings, published on the pre-print server medRxiv, provides the sector with recommendations to help reduce the risk for students, staff and the wider community.
This month, thousands of UK university students are due to start the 2020/21 academic term and will arrive on campus from across the UK and internationally. As COVID-19 continues to circulate around the globe, universities are actively developing plans to keep students, staff and the wider community safe, while providing a high-quality student experience.
The team, led by Drs Ellen Brooks-Pollock and Hannah Christensen from the NIHR Health Protection Research Unit in Behavioural Science and Evaluation at University of Bristol and part of Bristol UNCOVER, conducted a rapid review of mathematical modelling studies looking at how coronavirus might spread in a university setting and what mitigation strategies could be most useful in helping to reduce it.
The team reviewed five studies, four from the US and one from the UK, and developed a new, detailed epidemic model based on UK student data. Their investigations considered testing, contact tracing, quarantine strategies, and other non-pharmaceutical interventions.
Their analyses provided the following recommendations to policy makers and the higher education sector:
- Multiple interventions will be required to enable universities to respond quickly to any evolving increases in Sars-CoV-2 cases, which include reducing peoples’ contacts (within residences and across the university community), effective testing, tracing and quarantine of individuals.
- Students and staff will need to closely adhere to the national guidance around social distancing and hand washing, and will need clear advice on what to do if they are symptomatic or asked to quarantine to help avoid large number of cases in the university community.
- Policies aimed at reducing how many people individuals come into contact with, and the risk of transmission during any face-to-face contacts, are critical. This could include moving teaching online, social distancing, and the correct use of face coverings.
- Limiting contacts, with reduced face-to-face teaching and reducing the size of living circles, was the single most effective control option.
- If mass testing is used, it needs to be frequent, with persons without symptoms being tested weekly or more often.
Dr Hannah Christensen, Senior Lecturer in Infectious Disease Mathematical Modelling in Bristol Medical School, said: “Mathematical models are currently being used to help understand the evolving COVID-19 pandemic and to inform prevention and control strategies. Many UK universities are planning for students to return to campus in autumn 2020 in a blended teaching model, for example with large lectures replaced with online teaching and small group practical classes, delivered with social distancing measures in place. Other UK universities are considering alternative teaching models, including some planning full online learning for at least the first term.
“In the absence of a vaccine, managing COVID-19 within a university setting presents unique challenges. However, our results have shown certain interventions can be effective. Minimising face-to-face contacts and lowering the risk of virus transmission when people do meet, through physical distancing, the use of face coverings and good hand hygiene, all help reduce the spread. Testing, with contact tracing and quarantining, also plays a critical part in controlling outbreaks.”
Dr Ellen Brooks-Pollock, Senior Lecturer in Veterinary Public Health and Infectious Disease Modelling at the University of Bristol, added: “Our findings clearly show that multiple mitigation interventions are needed to help universities respond effectively to any increase in cases. Some interventions can be implemented with limited additional resources, others, such as mass testing would require additional capacity. Mass testing of all students could be effective but is dependent on regular testing and effective self-isolation. In addition, there are big data gaps that need to be filled in order to characterise transmission in this population, such as how infectious cases with mild symptoms are.”
The studies were funded by National Institute for Health Research (NIHR) and the University of Bristol.
COVID-19 transmission in a university setting: a rapid review of modelling studies by Hannah Christensen, Ellen Brooks-Pollock et al in medRxiv
High COVID-19 transmission potential associated with re-opening universities can be mitigated with layered interventions by Ellen Brooks-Pollock, Hannah Christensen et al in medRxiv
Please note these are preprints, so are preliminary pieces of research that have not yet been through peer review and have not been published in a scientific journal – so this is early data.
About the NIHR
The National Institute for Health Research (NIHR) is the nation’s largest funder of health and care research. The NIHR:
- funds, supports and delivers high quality research that benefits the NHS, public health and social care
- engages and involves patients, carers and the public in order to improve the reach, quality and impact of research
- attracts, trains and supports the best researchers to tackle the complex health and care challenges of the future
- invests in world-class infrastructure and a skilled delivery workforce to translate discoveries into improved treatments and services
- partners with other public funders, charities and industry to maximise the value of research to patients and the economy.
The NIHR was established in 2006 to improve the health and wealth of the nation through research, and is funded by the Department of Health and Social Care. In addition to its national role, the NIHR supports applied health research for the direct and primary benefit of people in low- and middle-income countries, using UK aid from the UK government.
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